Research studies near you are looking at new approaches for Parkinson's OFF time. Take the two-minute questionnaire

Parkinson's research, enrolling now

When your medication wears off before the next dose is due.

Research studies near you are looking at investigational treatments for adults with Parkinson's who have OFF time. Many are add-on studies, where you keep your current medication.

Start the two-minute questionnaire

Confidential. No obligation. No cost.

Studies are looking for people who:

  • Are adults diagnosed with Parkinson's disease
  • Take levodopa or other Parkinson's medication
  • Have OFF time, when a dose wears off early

Each study has its own full criteria. A study doctor makes the final decision.

See if you may qualify

Two minutes, then the research site takes it from here

  1. 1Answer a few questions about your diagnosis and medications.
  2. 2If you may be a fit, your answers go to the research site nearest you.
  3. 3Their study team calls you to talk it through.
  • Confidential
  • No obligation
  • No cost
  • No insurance needed

Answering for a parent or partner? The form asks.

By submitting, you agree that Clinical Enrollment may share your answers and contact details with the research site nearest you, and that the site's study team may call, text and email you about this research. Consent isn't a condition of taking part. Message and data rates may apply. Reply STOP to opt out. Privacy policy.

Parkinson's questionnaire

About this research

What OFF time is, and what researchers are looking at

Over the years, each dose of levodopa wears off sooner. The slowness, stiffness or tremor come back before the next dose is due. That's OFF time.

Much of today's research looks at treatments that may shorten OFF time without making dyskinesia worse. Each study tests its own approach, and the site explains yours before you agree to anything.

ONONON OFFOFFOFF DOSE
An example day. Each dot is a dose, and above the dashed line the medication is working. The shaded gaps are OFF time.

How it works

Four steps, and our part is the first two

1

Questionnaire

About two minutes, right here.

2

Sent to a site

Only if you may be a fit.

3

The site calls you

Their study team talks it through.

4

Screening visit

Consent first, then a few checks.

The full step-by-step

Parkinson's disease, briefly

A loss of the brain cells that make dopamine

The body needs dopamine for smooth, coordinated movement.

Today

Levodopa

Replaces dopamine. The main treatment.

Today

Add-on medicines

Help each dose last longer.

Today

Deep brain stimulation

A surgery that helps some people.

Research

New approaches

Aimed at shorter OFF time without more dyskinesia.

Sources: The Michael J. Fox Foundation, Mayo Clinic.

Questions

What people with Parkinson's ask us most

The research site answers the rest when they call. More general questions here.

Do I need to stop taking my levodopa?

Usually not. Most of this research adds a treatment, or a placebo, to your usual medication.

I don't have OFF time yet. Can I join?

Probably not for this research. Studies for earlier Parkinson's open from time to time.

Is there a placebo?

Many studies use one. If yours does, the consent form says so and gives you the odds.

Will I keep a diary?

Often. Many studies ask you to note when you're ON and OFF at home. The site shows you how.

Can my care partner come with me?

Yes, and we'd encourage it.

Does it cost anything?

No. Study care and visits are provided at no cost, and many studies pay for time and travel.

Does finishing the questionnaire mean I'm in?

No. It's a first match. A study doctor decides at a screening visit.

Who we are

A real company, with an address, that you never pay

Clinical Enrollment, LLC connects people with research sites near them. We're at 105 Monticello Ave, Unit 100, Charlottesville, Virginia. We don't run studies, and we'll never ask you for money.

How to check any study, including this one. Questions: help@clinicalenrollment.com

See if you qualify